Insulin and Leptin are two very important hormones that regulate our blood sugar and appetite.
Insulin is a protein hormone secreted by a group of cells inside the pancreas. These cells are called islet cells. When carbohydrates (sugars) enter the bloodstream, insulin is released to help the cells absorb the sugars. Think of insulin as the key that opens up the cells to receive energy. When you eat to much sugary foods, the pancreas goes into full gear to produce enough insulin to clean up the sugars from the bloodstream. Over time, the pancreas gets tired of overproducing insulin and either gets destroyed or burns out. A symptom that your pancreas is burning out is insulin resistance.
Being overweight and eating processed sugary foods can lead to insulin resistance and Type 2 diabetes.
Leptin comes from the Greek word leptos which means thin. It is a key protein hormone that helps regulate appetite and metabolism. Leptin is made in your white adipose tissue or stored fat. Once it's released from the fat, it travels to the brain using the bloodstream. Leptins signal to the brain when you are no longer hungry. If the hormone isn't working properly in some people, it leads to a constant desire for food. In obese people there is a high concentration of leptin in their body but they are resistant to the effects of it. Leptin also plays a role in regulating the function of your brain immune system and the coordination of hormones in your body- thyroid, adrenal function and stress and reproductive.
Losing weight is a very crucial aspect of taking control of this hormone. The more fat you have around your body, the higher likelihood of being leptin resistant.